Zesty Cajun Garlic Chicken

Featured in: Everyday Flavors

This dish features juicy chicken pieces and tender cheese tortellini enveloped in a luscious creamy sauce spiced with Cajun seasoning, garlic, and Parmesan. The addition of sautéed onions and bell peppers adds depth and sweetness, balanced by smoky paprika and fresh parsley garnish. Perfect for a quick savory dinner that combines vibrant flavors with satisfying textures, this meal brings a delightful fusion of American and Italian influences right to your plate.

Updated on Sun, 09 Nov 2025 13:14:00 GMT
Zesty Cajun Garlic Parmesan Chicken Tortellini in a creamy sauce with fresh herbs.  Save
Zesty Cajun Garlic Parmesan Chicken Tortellini in a creamy sauce with fresh herbs. | oventhyme.com

A vibrant and flavorful pasta dish featuring tender chicken, cheesy tortellini, and a creamy Cajun garlic Parmesan sauce. Perfect for a quick weeknight meal with a spicy kick.

I first made this Cajun garlic Parmesan chicken tortellini on a busy Monday night when I was craving something creamy and comforting yet full of zest. The combination became an instant favorite in our dinner rotation.

Ingredients

  • Chicken breasts: 2 large boneless, skinless, cut into bite-sized pieces
  • Cheese tortellini: 500 g (18 oz) refrigerated
  • Garlic: 3 cloves, minced
  • Red bell pepper: 1 small, diced
  • Yellow onion: 1 small, diced
  • Heavy cream: 1 cup (240 ml)
  • Parmesan cheese: 1/2 cup (50 g) freshly grated
  • Unsalted butter: 2 tablespoons
  • Cajun seasoning: 1 tablespoon
  • Smoked paprika: 1/2 teaspoon
  • Black pepper: 1/2 teaspoon
  • Salt: 1/2 teaspoon, plus more to taste
  • Olive oil: 2 tablespoons
  • Fresh parsley: 2 tablespoons chopped, for garnish
  • Optional: Extra grated Parmesan for serving

Instructions

Cook the tortellini:
Bring a large pot of salted water to a boil. Cook tortellini according to package instructions. Drain and set aside.
Sauté the chicken:
Heat 1 tablespoon olive oil in a large skillet over medium-high heat. Add chicken pieces, season with half the Cajun seasoning, salt, and pepper. Sauté until browned and cooked through, about 5-7 minutes. Remove chicken from skillet and set aside.
Cook vegetables:
In the same skillet, add remaining olive oil and butter. Sauté onion and bell pepper for 3-4 minutes until softened. Add garlic and cook for 30 seconds until fragrant.
Make the sauce:
Sprinkle in remaining Cajun seasoning and smoked paprika. Stir, then pour in the heavy cream. Bring to a gentle simmer, stirring frequently.
Add cheese:
Add Parmesan cheese and stir until melted and sauce is smooth. Taste and adjust seasoning if needed.
Combine:
Return chicken to the skillet, along with cooked tortellini. Toss gently to coat everything in the sauce.
Finish and serve:
Cook for an additional 2-3 minutes until heated through. Serve garnished with fresh parsley and extra Parmesan if desired.
Creamy Zesty Cajun Garlic Parmesan Chicken Tortellini topped with grated cheese and parsley.  Save
Creamy Zesty Cajun Garlic Parmesan Chicken Tortellini topped with grated cheese and parsley. | oventhyme.com

This dish has become a go-to family comfort meal for us, perfect for sharing at the table on busy evenings when we want something special without too much effort.

Required Tools

Large pot, large skillet, chefs knife, cutting board, wooden spoon or spatula, measuring cups and spoons.

Allergen Information

Contains: Wheat (tortellini), Milk (cream, Parmesan, butter), Eggs (tortellini may contain eggs). Double-check tortellini packaging for specific allergens.

Nutritional Information (per serving)

Calories: 620, Total Fat: 29 g, Carbohydrates: 53 g, Protein: 38 g

Delicious Zesty Cajun Garlic Parmesan Chicken Tortellini served with crusty bread on the side. Save
Delicious Zesty Cajun Garlic Parmesan Chicken Tortellini served with crusty bread on the side. | oventhyme.com

Enjoy this creamy, zesty tortellini hot and garnish with extra Parmesan for a crowd-pleasing finish. It's a perfect fusion for spice and pasta lovers alike.

Kitchen Guide

What type of chicken is best for this dish?

Boneless, skinless chicken breasts cut into bite-sized pieces work best for even cooking and tenderness.

Can I use other pasta instead of tortellini?

Yes, cheese-filled tortellini gives richness, but pasta like gnocchi or ravioli can be substituted for similar texture.

How can I adjust the spice level?

Increase or reduce Cajun seasoning or add a pinch of cayenne pepper or red pepper flakes to modify the heat.

Is there a non-dairy alternative for the creamy sauce?

You can try coconut cream or cashew cream in place of heavy cream for a dairy-free option, though flavor will vary.

What side dishes pair well with this meal?

Crusty bread is ideal to soak up sauce, and a crisp white wine like Sauvignon Blanc complements the flavors beautifully.

Can I replace chicken with seafood?

Yes, shrimp can be used as a tasty alternative for a seafood variation of the dish.

Zesty Cajun Garlic Chicken

Tender chicken and cheese tortellini in a creamy, spicy Cajun garlic Parmesan sauce.

Prep duration
15 min
Kitchen time
25 min
Complete duration
40 min
Created by Grace Mitchell


Skill level Easy

Heritage American/Italian Fusion

Output 4 Portions

Dietary requirements None specified

What you'll need

Proteins

01 2 large boneless, skinless chicken breasts, cut into bite-sized pieces

Pasta

01 18 ounces refrigerated cheese tortellini

Vegetables & Aromatics

01 3 cloves garlic, minced
02 1 small red bell pepper, diced
03 1 small yellow onion, diced

Dairy

01 1 cup heavy cream (240 ml)
02 1/2 cup freshly grated Parmesan cheese (50 g)
03 2 tablespoons unsalted butter

Spices & Seasonings

01 1 tablespoon Cajun seasoning
02 1/2 teaspoon smoked paprika
03 1/2 teaspoon black pepper
04 1/2 teaspoon salt, plus additional to taste

Oils & Garnish

01 2 tablespoons olive oil
02 2 tablespoons chopped fresh parsley (for garnish)
03 Optional: extra grated Parmesan for serving

Method

Phase 01

Cook tortellini: Bring a large pot of salted water to a boil. Cook tortellini according to package instructions. Drain and set aside.

Phase 02

Sauté chicken: Heat 1 tablespoon olive oil in a large skillet over medium-high heat. Season chicken pieces with half the Cajun seasoning, salt, and pepper. Sauté until browned and cooked through, about 5 to 7 minutes. Remove chicken and set aside.

Phase 03

Cook aromatics: In the same skillet, add remaining olive oil and butter. Sauté diced onion and bell pepper for 3 to 4 minutes until softened. Add minced garlic and cook for 30 seconds until fragrant.

Phase 04

Create sauce base: Stir in remaining Cajun seasoning and smoked paprika. Pour in heavy cream and bring to a gentle simmer while stirring frequently.

Phase 05

Incorporate cheese: Add grated Parmesan cheese and stir until melted and the sauce is smooth. Adjust seasoning as needed.

Phase 06

Combine ingredients: Return cooked chicken to the skillet along with the tortellini. Toss gently to coat everything evenly with the sauce.

Phase 07

Finish and serve: Cook for an additional 2 to 3 minutes until heated through. Serve garnished with fresh parsley and extra Parmesan if desired.

Kitchen tools needed

  • Large pot
  • Large skillet
  • Chef's knife
  • Cutting board
  • Wooden spoon or spatula
  • Measuring cups and spoons

Allergy notes

Always review ingredients for potential allergens and seek professional medical advice when uncertain.
  • Contains wheat (tortellini), milk (cream, Parmesan, butter), and eggs (tortellini may contain eggs). Verify individual packaging for allergen details.

Nutrition breakdown (per portion)

Values shown are estimates only - consult healthcare providers for specific advice.
  • Energy: 620
  • Fats: 29 g
  • Carbohydrates: 53 g
  • Proteins: 38 g